In February 2009, the BC Prenatal Genetic Screening Program adopted a serum-based approach to prenatal genetic screening with nuchal translucency (NT) ultrasound added for women at higher risk of having a fetus with Down syndrome or trisomy 18 and women with multiple gestations. Since the launch of the program, we have made significant progress in the implementation of NT ultrasound sites increasing our capacity to offer Integrated Prenatal Screening (IPS) (NT plus first and second trimester serum markers) to a larger proportion of women at higher risk. In addition, our commitment to provide screening that is evidence-based means that we must adjust our approach as new evidence is published.

The January 2010 Update focuses on:

• Changes to the Guideline: Prenatal Screening for Down Syndrome, Trisomy 18 and Neural Tube Defects
• Information on current utilization
• Answers to Frequently Asked Questions
• Practical points

The tables and algorithms have also been updated and REPLACE those distributed with the Guideline in February 2009. The updated Guideline reflecting these January 2010 changes is available for download.